Current concepts of ectopic nodal inclusions with special emphasis on nodal nevi

نویسندگان

چکیده

Nodal inclusions of ectopic tissue within lymph nodes are seen comparatively often in dermatopathology and general pathology. Glandular nonglandular epithelium, as well melanocytic nevi can be observed represent mostly incidental findings without any relevance. The main challenge reporting these morphologic features is to differentiate such benign from metastatic settlements distinct organ tumors. As sentinel node biopsy dissection have become standard procedure clinical oncology an immense impact, the correct evaluation nodal indispensable avoid undertreatment or overtreatment patients. In addition, genesis has not yet been satisfactorily clarified. Two concepts laid out: theory metastases migration arrest theory. However, neither so far able answer following questions: Why do we find more patients with melanoma who had a than melanoma, why deep visceral nodes? We present comprehensive review current knowledge on inclusions, proposing concept for pathogenesis nevi, questions.

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ژورنال

عنوان ژورنال: Journal der Deutschen Dermatologischen Gesellschaft

سال: 2021

ISSN: ['1610-0379', '1610-0387']

DOI: https://doi.org/10.1111/ddg.14521